This project proposes an immunotherapeutic approach for the treatment of acute lymphoblastic leukemia. This is done by transducing self-regenerating hematopoietic stem cells, with an anti-CD22 gene and a promoter to maximize the expressivity of the gene in only cytotoxic immune cells. The gene codes for a receptor targeting CD22: a protein found on the surface of acute lymphoblastic leukemia cells.
Gabriel Dayan
This project proposes an immunotherapeutic approach for the treatment of acute lymphoblastic leukemia. This is done by transducing self-regenerating hematopoietic stem cells, with an anti-CD22 gene and a promoter to maximize the expressivity of the gene in only cytotoxic immune cells. The gene codes for a receptor targeting CD22: a protein found on the surface of acute lymphoblastic leukemia cells.